Ion Layer

First-time buyer's checklist

Not all NAD+ patches are the same. 5 things to check before you buy.

Two products can both say “NAD+ patch” on the box and have almost nothing in common. Here is what to look for on the label, in the technology, and in the box, so you know what you are actually buying.

Try Risk Free Read the 5 checks
A man wearing an Ion Layer NAD+ iontophoresis patch on his arm after training
500mg NAD+ per patchMixed fresh from powder, delivered by a powered iontophoresis patch.
“Ion Layer NAD+ patches are my go-to NAD+ solution for at-home infusions. Also super convenient for getting an extra boost of energy and recovery while I’m traveling.”Ben GreenfieldHealth biohacker, best-selling author
“NAD therapy helped me recover from COVID. Ion Layer patches are a great alternative to IVs because they are much cheaper and faster.”Dr. Molly MaloofHealth biohacker, best-selling author
“Been relying on the NAD+ patches every two weeks or so and my energy levels have been unreal.”Taylor RappNFL safety
“I woke up in the green on my Whoop after wearing the patch, even after a 24 hour travel day and missing a night of sleep.”Omar GonzalezPro soccer player

What to check

Five questions worth asking before you pay for any patch.

Run these on whatever you are considering. Each one ends with how the Ion Layer kit answers it, so you can compare like for like.

1

What is actually in it

The name on the front is not the ingredient list. A lot of what is sold as a “NAD+ patch” carries a precursor instead, a molecule the body has to convert before it becomes NAD+ at all, and often in single-digit milligrams. Turn the box over and read the panel: you are looking for the molecule itself, and the dose per patch, not per box.

The Ion Layer kit: a vial of NAD+ powder beside the iontophoresis patches
The vial is the product. The patch is how it gets in.

How the Ion Layer kit answers it

  • 500mg of NAD+ per patch, not a precursor, and that figure is per patch.
  • It ships as powder in a sealed vial, one vial per patch.
2

How it gets through skin

Skin is a barrier, and that is its job. A sticker holds an ingredient against the skin and leaves the rest to chance. Ask what is doing the work of moving the molecule through, and whether there is anything in the patch besides adhesive.

The Ion Layer iontophoresis patch worn on an upper arm
A single-use battery sits inside the patch itself.

How the Ion Layer kit answers it

  • Each patch uses iontophoresis: a small one-time-use battery powers a mild current.
  • That current is what carries the NAD+ through the skin, steadily, over the wear time.
3

Who signed off on it

Anything you can add to a cart and receive with no questions asked has, by definition, had no one look at your case. That is convenient, and it is also the trade. Check whether a licensed provider is involved at any point, and what the product is actually classified as.

A man wearing the patch at home during a normal working day
The form takes about five minutes and needs a photo ID.

How the Ion Layer kit answers it

  • The patch is a class 2 medical device and is prescription only.
  • You complete a short form after purchase, and a licensed provider reviews it within 24 hours.
4

How it is prepared

NAD+ starts to degrade once it is sitting in solution. So a product that arrives pre-mixed has been degrading since the day it was filled, through the warehouse and the shelf. Ask in what state the ingredient arrives, and who mixes it.

A customer with the patch applied at home
Mix, apply, wear. Then throw the patch away.

How the Ion Layer kit answers it

  • You mix the powder with the sterile water in the kit, right before you wear it.
  • Each patch is worn 12 to 14 hours, then disposed of. Nothing is reused.
5

What is in the box

A low price per patch means little if the routine asks for one every day. Work out what a month actually costs, and what you have to buy again to keep going. Count the patches, and count the days they cover.

An Ion Layer customer wearing the patch at a race
One kit covers a 30 day protocol.

How the Ion Layer kit answers it

  • 6 patches, 6 vials of NAD+ powder, 6 sterile solution tubes.
  • One patch every 5 days, so a kit is a 30 day protocol, not a daily habit.

Measured, not estimated

What it did to NAD+ levels in testing.

In clinical testing, participants using Ion Layer's iontophoresis patches saw intracellular NAD+ levels rise from 20.9 to 31.0, a 48% increase, in 7 days of use.

Ion Layer's own clinical testing. Individual results vary.

Chart of intracellular NAD+ levels rising from 20.9 to 31.0 over seven days

Now that you know what to look for

Start with the kit the checklist describes.

High Dose NAD+ Patches
Most popular

High Dose NAD+ Patches

The kit the five checks describe: 500mg NAD+ per patch, powered delivery, mixed fresh.

$499.00 $649.00 Save $150.00

Monthly delivery. Cancel or modify anytime.

  • 6 iontophoresis patches
  • 6 vials of 500mg NAD+ powder
  • 6 sterile solution tubes for mixing
  • Provider review within 24 hours

30-day money-back guarantee on first orders. Free shipping.

NAD+ & Glutathione Combo Patches
Add detox support

NAD+ & Glutathione Combo Patches

The same patch and the same routine, with glutathione alongside the NAD+.

$699.00 $849.00 Save $150.00

Monthly delivery. Cancel or modify anytime.

  • Everything in the High Dose kit
  • Glutathione in the same patch

Same provider review and the same guarantee.

Straight answers

Before you decide.

Why does it need a prescription?+
The transdermal patch is a class 2 medical device, so it cannot be sold over the counter. You complete a short form after purchase, which takes about five minutes and needs a photo ID, and a licensed provider reviews it within 24 hours.
Why is it powder and not a ready-made patch?+
NAD+ begins to degrade once it is in solution. Shipping it as powder and mixing it with the sterile water in the kit means it is made up right before you wear it, not months earlier.
How often do I wear one?+
One patch every 5 days, worn for 12 to 14 hours. A kit holds 6 patches, which is a 30 day protocol. Avoid soaking the patch, and use warm water and soap when you take it off.
What if it does not work for me?+
First orders carry a 30-day money-back guarantee. Shipping is free, and you can cancel or modify the monthly delivery at any time.
What is actually in the box?+
6 iontophoresis patches, 6 vials of 500mg NAD+ powder and 6 sterile solution tubes for mixing, plus the prescription form you complete after checkout.
An Ion Layer customer wearing the patch at home

You have the checklist

Know what you are buying, then try it risk free.

500mg of NAD+ per patch, mixed fresh, delivered by a powered patch, reviewed by a licensed provider. 30 days to change your mind.

Try Risk Free
High Dose NAD+ Patches · $499.00Monthly, save $150.00 · 30-day guarantee