Ion Layer patches are manufactured with latex free components and are hypoallergenic. On occasion, Ion members may have some skin irritation from the adhesive or medication that is applied to the skin. If you notice any irritation, please consult with your Ion physician or email us at hello@ionlayer.com.

If you've had NAD+ IVs before you'll know it is common to feel cramping, nausea, and intense internal pain. Because the patches infuse the same amount of NAD+ over 14 hours instead of 45 minutes, those symptoms are nearly reduced to nothing. Those with sensitive skin may notice a slight reaction the adhesive patch, but nothing more than you would with a bandaid. You might lose some arm hairs too, but that's more a feature than a bug. Read more about the Ion Patch with our technical overview here: https://www.ionlayer.com/legal-pages/patch-technical-overview.

Those with sensitive skin may notice a slight reaction the adhesive patch, but nothing more than you would with a bandaid. You might lose some arm hairs too, but that's more a feature than a bug. You may notice extreme cramping and nausea with IVs, but should have very limited reaction to our patches.

Yes. Ion Layer uses patches that are extremely flexible and adhere well to the skin under normal daily activities, including exercise. The patches are designed to withstand a lot of motion motion and weight-bearing exercises. If you are extremely active, be sure to use the Ion Layer adhesive (black) cover to keep the patch in place.

If you need to shower while wearing the patch, we recommend to avoid putting the patch under the water stream as much as possible. If the patch does get wet, just gently pat it dry with a towel. Do not immerse the patch in bathwater, as the soapy water will loosen the adhesive.

Yes, you can wear the patch while you sleep. I personally wear it when I sleep and just remove it in the morning. We recommend wearing the patch for 14 hours and then removing it since the NAD+ will all be delivered within that 14-hour window and as a result it wearing it overnight has been one of our favorite times to wear them.

Yes. The iontophoresis patches contains a small battery operated device that facilitates the absorption of NAD+ through skin into the bloodstream. The patches are considered a medical device due to this mechanism and, therefore, are only available by prescription. Our network of physicians will review your intake form, schedule a virtual consult, and will help you decide if IonLayer is a good fit or not for you. Upon their recommendation they will prescribe IonLayer and it will ship from our partner pharmacy straight to your door.

Nope! No needles here. Iontophoresis patches use a small one-time use battery to power the current that pushes the NAD+ across your skin and to your bloodstream. The best part? You don't feel a thing. No tingling, pinching, shocking, zapping and best of all -- no needles.

It is best to remove an Ion Layer patches after getting them wet. While it is common for Ion members to remove their Ion Layer patch in the shower or bath, the most important thing to remember is to use some soap and some water to loosen the adhesive before removal.

Minor skin reddening beneath the area where the patch was applied is a common occurrence and typically subsides after a brief period. Ion Layer utilizes patches that are engineered to be hypo-allergenic, yet the adhesive tapes may occasionally cause skin irritation, leading to minor alterations in skin color that will normalize over time. Occasionally, patients may have a localized reaction to the medication applied to the treatment site. If you observe an unusual reaction in the treatment area or experience any abnormal discomfort or pain, promptly remove the patch with soapy water, thoroughly clean the area, and inform us at hello@ionlayer.com. To reduce the risk of skin irritation, it's recommended to rotate the area where you apply the patch and to not apply the patch to the same area on your body within 10 days of the last patch and to gently remove the patch using soap and water during a shower or bath. After drying, apply lotion to the treated area.

Yes! There are hundreds of research articles that validate the use of NAD+ to boost levels in vivo that lead to increased life span, improved metabolic health, lower inflammation, increased energy, better focus, and more. See the section on our homepage for benefits of NAD+ to see linked research. We are currently working on a public database of research and will be sharing more of our findings soon.

Sounds crazy, but without NAD+ there would cease to be life. Your body produces NAD+ naturally from B vitamins and via making energy, so it's not a new or foreign compound to the body. There are also other natural ways to make NAD+, such as through nutrition, exercise, and heat exposure.

It is a coenzyme that is critical for every cell in your body and the majority of your metabolic processes. A coenzyme is a substance that drives processes forward. It carries electrons around your body that are critical for energy, metabolism, DNA repair, and more. It is critical for life and buffers many physiological processes. As you age and succumb to inflammatory processes, natural NAD+ production decreases.

Place the patch anywhere where hair will not interfere with mild adhesive. Common locations are upper arm, abdomen, back, and thigh.

IonLayer currently works with Curexa Pharmacy and HealthSmart Pharmacy and their partner pharmacy. To consult or ask questions of your pharmacist, you can reach out to Curexa Pharmacy via mail at 3007 Ocean Heights Avenue, Egg Harbor Township, NJ 08234 or call them at 855.927.0390 and HealthSmart Pharmacy (partner pharmacy) via mail 9197 Cleveland Road Clayton, NC 27520 or call them at 919.359.1474.

NAD+ starts degrading as soon as it is made into a solution. If you'd had any NAD+ that isn't mixed right before you use it, you are likely getting a very low amount, if at all of the active compounds. We supply your raw NAD+ with sterile water to maximize the potency to make sure you get the most out of your treatment as humanly possible.

Identity verification is required by our Telehealth partner to ensure that there is a real person behind a process and proves that they are who they are claiming to be. This protects our partner providers from anyone attempting to act on someone else's behalf without authorization or creating false identities.

Precursors to NAD+ have been shown to be effective for some, but many do not experience the benefits of increased NAD+ levels as the amounts are too low. The precursors have to go through many steps, which depending on individual biology, may not be efficient or lead to actually increased levels of NAD+. High dose NAD+ administered directly to the bloodstream, as in IV or iontophoresis applications, leads to a much higher and sustained elevation of serum NAD+ than precursors.

Ion Layer uses patches with a very low level of electric current. There is normally no feeling or sensation when wearing Ion Layer. On occasion, Ion members report a “slight tingly” feeling during drug delivery. If for some reason you feel any unusual discomfort or pain, simply remove the patch with soapy water, clean the area well, and notify us at hello@ionlayer.com.