GLP-1 WEIGHT LOSS PROTOCOLS

Precision GLP-1 Pens. Physician-Prescribed.

First-generation and second-generation compounded GLP-1 peptides, delivered in a dial-to-dose precision injector pen. Choose your medication, select your dosing strategy, and start your protocol.

I WANT MAX CLINICAL WEIGHT LOSS I WANT Maintenance + METABOLIC BENEFITS
U.S. Licensed Physicians
FDA-Inspected 503A Pharmacies
No Hidden Membership Fees
Flat Pricing Across All Dose Tiers
DECISION GUIDE

Semaglutide vs. Tirzepatide

The right medication depends on your goals, your history with GLP-1s, and how your body responds. Here is a plain-language breakdown.

FIRST-GENERATION GLP-1

Compounded Semaglutide + Glycine

Mechanism

Single receptor (GLP-1 only)

Primary Goal

Appetite control & sustained energy

Additive

Glycine — supports lean muscle preservation

Best For

First-time GLP-1 users, weight maintenance, energy optimization

SECOND-GENERATION DUAL-ACTION

Compounded Tirzepatide + Glycine

Mechanism

Dual receptor (GLP-1 + GIP)

Primary Goal

Maximum weight loss & body recomposition

Additive

Glycine — supports lean muscle preservation

Best For

Advanced users, biohackers, significant weight loss goals

DOSING STRATEGY

Microdosing vs. Standard Clinical Dosing

Not sure which dosing protocol is right for you? Your Ion Layer physician will guide the final decision, but here is how to think about it.

Microdose Protocol

A gentler, more gradual approach to GLP-1 therapy. Ideal for those who want to minimize side effects, maintain current progress, or ease into the medication.

New to GLP-1 medications

Sensitive to nausea or GI side effects

Goal is maintenance, not aggressive loss

Biohacker or metabolic optimization focus

Prefer a slower, more sustainable protocol

View Microdose Protocols

Standard Clinical Dose Protocol

The standard titration schedule used in clinical settings. Designed for patients seeking significant, measurable weight loss results within a defined timeframe.

Significant weight loss is the primary goal

Have prior GLP-1 experience

BMI or metabolic markers require clinical intervention

Comfortable with standard titration pace

Want the most clinically studied protocol

View Standard Protocols
WHY ION LAYER

Physician-Guided. Pharmacy-Direct.

Every Ion Layer protocol is built on three pillars of safety and quality that most telehealth providers cannot match.

U.S. Licensed Physician Review

Every protocol begins with a comprehensive online medical intake. A U.S.-licensed physician reviews your health history to confirm GLP-1 therapy is safe and appropriate for you before any medication is dispensed.

FDA-Inspected 503A Pharmacies

Your medication is compounded in an FDA-inspected 503A pharmacy and undergoes third-party purity testing for potency, sterility, and endotoxicity before it ships. You receive a Certificate of Analysis with every order.

The Precision Injector Pen

Unlike competitors who ship vials and loose syringes, Ion Layer delivers your medication in a precision dial-to-dose injector pen. No mixing, no measuring, no guesswork. Just dial your dose and inject.

THE PROCESS

Start Your Protocol in 3 Steps

100% online. No in-person appointments. No membership fees.

1

Choose Your Plan

Select your medication (Semaglutide or Tirzepatide), your dosing strategy (Microdose or Standard), and your billing interval (Monthly, 3-Month, or 6-Month). Flat pricing — no upcharges as your dose increases.

2

Complete Your Medical Intake

Complete a comprehensive online health questionnaire. A U.S.-licensed physician reviews your intake — typically same day — and prescribes the protocol that is safe and appropriate for your goals.

3

Start Your Protocol

Your precision injector pen ships directly from an FDA-inspected pharmacy to your door. Ongoing physician support is included. Adjust your dosing at any time at no extra charge. Cancel anytime.

Ready to Start Your Protocol?

Join thousands of patients who have taken a precision approach to metabolic health.

Understanding Compounded GLP-1 Weight Loss Medications

Compounded GLP-1 medications provide a personalized approach to medical weight loss. While brand-name medications are manufactured in mass quantities, compounded semaglutide and compounded tirzepatide are prepared in state-licensed 503A pharmacies based on a physician's specific prescription. This allows Ion Layer to include a targeted additive — Glycine — in every protocol, creating a more comprehensive metabolic program that supports lean muscle preservation and reduces common GI side effects.

Choosing the right GLP-1 protocol depends on your goals. First-generation semaglutide is a single-receptor agonist with a well-established clinical record. Second-generation tirzepatide adds GIP-receptor agonism for greater weight loss and metabolic regulation. Both are available in standard clinical doses or in Ion Layer's microdose protocols — designed for sustainable, gentler progress without the intensity of full titration.

Disclaimer: The statements on this page have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All treatment decisions are made by independent, U.S.-licensed medical providers based on clinical evaluation and individual health needs.

Prescription Required: Prescription medication is only available if prescribed after an online consultation with a healthcare provider. Physicians may prescribe compounded medications as needed to meet patient requirements or drug shortages. Results may vary and are most effective when combined with healthy lifestyle changes, including diet and exercise.

Trademark Notice: Ozempic® and Wegovy® are registered trademarks of Novo Nordisk. Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. Ion Layer is not affiliated with, endorsed by, or sponsored by Novo Nordisk or Eli Lilly. Ion Layer provides access to compounded medications exclusively through U.S.-licensed 503A pharmacies and does not sell brand-name Ozempic®, Wegovy®, Mounjaro®, or Zepbound®.