Two women taking mirror selfies wearing black outfits with patches on their abdomens.

Clinician reviewed

Feel steady energy and better sleep, without needles

A clean, wearable NAD+ patch many women use to support energy, sleep, skin, and stress. Gentle routine. No clinic time.

Often felt the same day, no jitters or crash

Clean label, ingredient transparency

Simple apply-and-go routine that fits busy mornings

Try risk-free for 30 days

Designed for real life

Your routine, made easier

Apply in under a minute, then go about your day

Wear 12–14 hours; remove before bed

Great for morning focus, pre-workout, travel, or stressful weeks

No needles
No pills to remember
Comfortable, skin-friendly wear.
Woman in a grey long-sleeve top taking a mirror selfie, wearing an Ion Layer patch on her abdomen.
What women often notice

How it may feel

GLP-1 medications reward consistency. Here is what the journey looks like.

  1. After 1 hour

    A lighter head and easier focus; a calm lift rather than a jolt

  2. After 3 hour

    Steadier energy; fewer dips; tasks feel smoother to finish

  3. By day’s end

    Less “3 pm crash”; travel or workout fatigue may feel lighter

  4. After a week

    Many report a more consistent rhythm, easier mornings, and better sleep quality

Gentle and clean by design

Safety and ingredients, up front

Transparent ingredient list and clean label

Steady release designed to avoid jittery spikes

Built to be routine-friendly; talk to your clinician if on medications or managing hormones

Woman outdoors holding an Ion Layer kit box, wearing a patch on her abdomen.

Value you can feel good about

Six at-home treatments for less than one IV visit

About $83 per treatment at home
No appointments or needle discomfort
Save time and stay consistent
Woman wearing an Ion Layer patch on her abdomen.

NAD+ Recovery Without The Clinic

  • Boost energy without the clinic visit
  • No-needle high dose infusions
  • Use anytime, anywhere
90-Day Energy Protocol

6 high-dose, needle-free NAD+ infusions.

Billed $180/month. Your kit ships today, and a fresh 90-day kit ships every 3 months. Manage your plan anytime in your account.
Board-Certified Doctors USA Pharmacies HSA/FSA Eligible
Kit Includes

Everything you need for 6 needle-free infusions, pre-measured and ready to go:

  • 6 high-dose transdermal patches
  • 6 pre-measured NAD+ vials (500mg each)
  • Mixing and application solutions
  • Protective adhesive covers

No measuring, no guesswork.

Our transdermal patches are considered a class 2 medical device. We handle it all for you! All you do is complete a 5 minute form after purchase (requires ID). This is required in order to receive your kit.

Free shipping on all orders. Manage your plan anytime in your account.

How to Use.

Ion Layer uses medical transdermal patches to deliver NAD+ straight into the bloodstream in a non-evasive way.

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1

Apply to clean, dry skin on upper arm or torso

Mix the compound with the provided sterile water solution.

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2

Wear during your day; hydrate well

Mix the compound with the provided sterile water solution.

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3

Remove after 12–14 hours; repeat per guidance

Mix the compound with the provided sterile water solution.

Frequently Asked Questions

Why do the patches require a prescription?

Our transdermal patches are considered a class 2 medical device. We handle it all for you! All you do is complete a 5 minute form after purchase (requires ID). This is required in order to receive your kit.

Our patches use iontophoresis — a clinically proven method that uses a mild electrical current to drive molecules through the skin and into your bloodstream. This bypasses the digestive system for superior absorption compared to oral supplements.

Iontophoresis patches deliver compounds directly into the bloodstream, bypassing the GI tract. Transdermal delivery achieves significantly higher bioavailability than oral supplements, which lose potency through digestion.

IV therapy typically costs $400–$700 per session. Ion Layer patches start at $83 per infusion with a monthly subscription — making them up to 5X cheaper with no clinic visit required.

Yes. Our patches are physician-formulated, manufactured by licensed pharmacies (Curexa Pharmacy and HealthSmart Pharmacy), and verified by LegitScript. Iontophoresis is a well-established medical technology used in clinical settings for decades.

Most users experience no side effects. Some may notice mild skin redness at the patch site, which typically fades quickly. If you experience any discomfort, remove the patch and contact us at hello@ionlayer.com.

Oral supplements must pass through the stomach. Ion Layer delivers directly through the skin, bypassing the digestive system entirely for more efficient absorption.

We offer a 30-day money-back guarantee. If you're not satisfied with your results, contact us at hello@ionlayer.com.

A gentler way to feel like you

Support energy, sleep, and calm with a simple, needle-free patch. Transparent ingredients. Easy routine. Many women notice a difference in how the day feels.