One pre-loaded pen replaces vials, syringes, and mixing. Dial your dose, inject, and get on with your day. No measuring. No prep. No guesswork.
Power Your Metabolism with the MOTS-c Pen
- Supports healthy glucose metabolism
- Supports endurance and exercise capacity
- Supports mitochondrial function as you age
About MOTS-c
MOTS-c is a 16-amino-acid peptide made by your mitochondria, the energy engines in your cells. Your body releases more of it when you exercise, and levels naturally fall with age.
It activates AMPK, your cells' energy sensor, which helps muscle take up glucose. Researchers study it as an exercise mimetic for that reason.
Is this safe?
MOTS-c is prescribed only after a licensed provider reviews your intake, and every pen is prepared by a LegitScript-certified US pharmacy.
Be clear-eyed about the science: MOTS-c research comes from cell, animal, and observational studies, and trials of administered MOTS-c in people have not been completed. MOTS-c is not FDA-approved.
- Tell your provider if you have diabetes or take glucose-lowering medication
- The most common side effect is mild redness or irritation at the injection site
- Not for use if you're pregnant, nursing, or being treated for cancer
- MOTS-c is on the WADA prohibited list. Skip it if you're tested in competitive sport
After checkout, you'll see a health questionnaire on the confirmation page. Fill it out and a licensed provider reviews your answers and writes your prescription within 24 hours.
MOTS-c Injections, Simplified

The Benefits of MOTS-c
Metabolic Health
MOTS-c activates AMPK, your cells' energy sensor, helping muscle take up and use glucose.
Endurance
Your body releases MOTS-c when you exercise. It is studied as an exercise mimetic for its role in endurance and energy.
Mitochondrial Support
MOTS-c is made by your mitochondria, and levels fall with age. Restoring it supports the cellular machinery that powers you.

Who MOTS-c Is For
Longevity-Focused Adults
You're 35+ and investing in metabolic health for the long run.
Active Performers
You want more energy and endurance from every workout.
Energy Seekers
Your energy has dipped with age and you want to support it at the cellular level.
How It Works
3 Simple Steps

Attach
Attach a fresh micro-needle to the pen.

Dial
Set your dose using the dial. No measuring. No mixing.

Inject
Press firmly on the dial to deliver your dose subcutaneously.
Quality You Can Trust
Third-party tested
Independently tested for purity and potency before it reaches you.
US pharmacies
Compounded by licensed, LegitScript-certified pharmacies in the United States.
Board-certified doctors
Every prescription is reviewed by a board-certified provider.
Frequently Asked Questions
Trusted By LegitScript
Ion Layer is certified by LegitScript — the leading provider of certification and monitoring services. They ensure a rigorous certification process, and many view their seal of approval as a benchmark for quality and safety.
How is this pen different from vials and syringes?
Instead of mixing vials and drawing doses with separate syringes, the injector pen is pre-loaded and simple. Dial your dose and inject. No measuring, no mixing.
How do I use the injector pen?
Attach a new micro-needle, dial the dose your provider prescribes, and press to inject just under the skin of your belly or thigh. Step-by-step instructions are in our Pen Guide.
Where do I inject?
Inject into the subcutaneous layer, just under the skin. Recommended areas: lower abdomen (2+ inches from your navel), upper glute, or outer thigh. Rotate sites to avoid irritation.
How often should I inject?
Your provider sets your dose and schedule based on your intake.
Do I need a prescription?
Yes. This is a compounded prescription product. Complete a short intake form after purchase and a licensed provider reviews it online.
Does it hurt?
Most people describe a quick click or pinch. The ultra-fine micro-needle is designed for comfortable delivery.
How do I store my pen?
Keep your pen cool in the refrigerator. Use it within 30 days of your first injection.
What if I have more questions or want to stop?
Dedicated support, a full refund if you aren't prescribed, and you can cancel a monthly subscription anytime before the pharmacy receives your next order.



